MP49-14 COMPARISON OF DIFFERENTIAL FUNCTIONAL OUTCOMES AFTER PARTIAL NEPHRECTOMY BETWEEN MODERATE AND HIGH COMPLEX RENAL TUMOR EVALUATED WITH DIETHYLENETRIAMINE PENTAACETIC ACID SCAN: A PROPENSITY SCORE MATCHED ANALYSIS

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy IV (MP49)1 Sep 2021MP49-14 COMPARISON OF DIFFERENTIAL FUNCTIONAL OUTCOMES AFTER PARTIAL NEPHRECTOMY BETWEEN MODERATE AND HIGH COMPLEX RENAL TUMOR EVALUATED WITH DIETHYLENETRIAMINE PENTAACETIC ACID SCAN: A PROPENSITY SCORE MATCHED ANALYSIS Hwanik Kim, Jin Noh, Jae Won Lee, Sang Hun Song, Hakju Jung Kwon Hakmin Sangchul Jong Oh, Seong jin Jeong, Sung Kyu Hong, and Seok-Soo Byun KimHwanik Kim More articles by this author , NohJin Noh LeeJae Lee SongSang Song KimHakju KimJung LeeHakmin LeeSangchul OhJong Oh JeongSeong Jeong HongSung Hong ByunSeok-Soo View All Author Informationhttps://doi.org/10.1097/JU.0000000000002075.14AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION OBJECTIVE: Renal function after partial nephrectomy (PN) depends on a complex clinical conditions including preoperative parenchymal quality, postop quantity, the recovery remaining nephrons from ischemic damages. However, natural history definitive predictors long-term RF PN in renal tumors with nephrometry score (RENAL) 7-9 (moderate complex, M) or 10-12 (high H) remain unclear. Thus, aim present study was compare functional outcomes evaluated diethylenetriamine pentaacetic acid (DTPA) scan Modification Diet Disease (MDRD) formula between M H tumors. METHODS: In 2004/01-2019/12, 471 patients RNS (M) 164 (H) who underwent were analyzed for outcomes. Glomerular filtration rate (GFR) measured DTPA scan, calculated GFR using formula, Trifecta/Pentafecta outcome, recurrence free survival (RFS), overall (OS) compared propensity matching analysis (PSMA). RESULTS: After PSMA, 156 cases each group matched without significant difference factor. At postoperative (postop) 1st year, there no Trifecta (p=0.320), MDRD-based (p=0.729), DTPA-based Pentafecta achievement (p=0.964) groups. 5 years, total (93.6% vs. 93.8%) operated kidney preservation (89.9% 81.7%) did not differ significantly (p>0.05). Kaplan-Meier showed differences Significant de novo chronic disease (CKD) stage ≥3 at year age (Hazard ratio (HR): 1.10, 95% CI: 1.03-1.17, p=0.005) (HR: 0.94, 0.91-0.98, p=0.001). CONCLUSIONS: High tumor can be treated deterioration. Postoperative kidney’s is preserved up 80% long term. should selectively performed caution avoid occurrence CKD. Source Funding: None © 2021 American Urological Association Education Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e881-e881 Advertisement Copyright & Permissions© Inc.MetricsAuthor Information Expand Loading ...